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Patients treated with both dosing regimens of ixekizumab had significantly greater levels of film allowance compared to placebo and to etanercept at the 12-week endpoint. Pelt leeway was unhurried via level peerless endpoints for psoriasis studies: the Psoriasis Parade-ground and Severity Directory (PASI) and the Static Physician Broad Assessment (sPGA).
 
In the interest patients treated with ixekizumab either every four weeks or every two weeks, between 78 to 90 percent of patients achieved at least a 75 percent reduction in PASI her own coin (PASI 75) at 12 weeks. Additionally, 31 to 41 percent of these patients achieved PASI 100, or clear bark, at week 12. For likeness, between 5 to 7 percent of patients treated with etanercept in the UNCOVER-2 and 3 studies achieved PASI 100.
Statistically valued improvements in skin room measures for patients treated with ixekizumab were observed as early as the oldest week when compared to either placebo or etanercept, and continued in the course week 12. In the UNCOVER-1 over, stiff levels of retort were maintained completely 60 weeks of treatment.
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Revisión actual del 19:06 21 oct 2014